Description

Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-3-Pyridinyl)- (9Ci) CAS NO 335665-28-6 is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. Its unique molecular structure, featuring a trifluoroacetyl group attached to a methoxypyridine ring, makes it a versatile intermediate for creating complex molecules with enhanced properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the trifluoromethyl group—a critical motif for improving metabolic stability, lipophilicity, and bioavailability in active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Acts as a building block for synthesizing specialty polymers and liquid crystals with unique optical and electronic properties.
• Fluorine Chemistry: A valuable reagent for introducing fluorine atoms into complex organic molecules, a key strategy in modern medicinal and materials chemistry.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in regulatory and research laboratories.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-3-Pyridinyl)- (9Ci)
CAS No.	335665-28-6
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-methoxy-3-pyridinyl)ethanone; 1-(2-Methoxy-3-pyridinyl)-2,2,2-trifluoroethanone; 2-Methoxy-3-pyridyl trifluoromethyl ketone; 3-Pyridinol, 2-methoxy-, 1-(2,2,2-trifluoroacetyl) derivative; 2,2,2-Trifluoro-1-(2-methoxypyridin-3-yl)ethan-1-one; TFMPK (abbreviation); CAS 335665-28-6
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 2,2,2-Trifluoro-1-(2-Methoxy-3-Pyridinyl)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.