Description

4-Bromo-1-(Bromomethyl)-2-(Trifluoromethyl)Benzene is a high-purity, multi-functional aromatic building block of significant commercial interest. This compound is valued for its unique combination of bromine and trifluoromethyl substituents, which impart specific reactivity and physicochemical properties. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of complex molecules with tailored functionalities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings, facilitating carbon-carbon bond formation.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, flame retardancy, or refractive index.
• Organic Synthesis & R&D: A versatile reagent for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	4-Bromo-1-(Bromomethyl)-2-(Trifluoromethyl)Benzene
CAS No.	335013-18-8
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	1,4-Dibromo-2-(trifluoromethyl)benzene, Bromomethyl Derivative; 2-(Trifluoromethyl)-1,4-dibromobenzene; 4-Bromo-α-bromo-2-(trifluoromethyl)toluene; 1,4-Dibromo-2-trifluoromethylbenzene; α,4-Dibromo-2-(trifluoromethyl)toluene; 2-Trifluoromethyl-1,4-dibromobenzene; Benzene, 4-bromo-1-(bromomethyl)-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-1-(Bromomethyl)-2-(Trifluoromethyl)Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.