Description

5,6-Dihydro Thymine-D6 is a stable isotope-labeled analog of thymine, a fundamental pyrimidine nucleobase. This deuterated compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic studies, and the synthesis of labeled nucleosides and nucleotides.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of thymine and related metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to elucidate metabolic pathways and degradation products.
• Synthetic Building Block: Serves as a key precursor in the synthesis of deuterium-labeled nucleosides, nucleotides, and oligonucleotides for research.
• Biochemical Research: Employed in enzymatic studies and as a tracer in nucleic acid research to investigate replication and repair mechanisms.
• Pharmaceutical Development: Supports drug discovery and development processes requiring isotopically labeled standards for regulatory bioanalysis.
• Environmental and Food Analysis: Applicable in residue analysis and contaminant tracking where high specificity and sensitivity are needed.

Basic Information

Product Name	5,6-Dihydro Thymine-D6
CAS No.	334473-42-6
Molecular Formula	C5H2D6N2O2
Molecular Weight	134.17 g/mol
Synonyms	Thymine-d6 (5,6-dihydro); 5,6-Dihydro-2,4(1H,3H)-pyrimidinedione-d6; 5-Methyl-2,4(1H,3H)-pyrimidinedione-5,6,6-d3; Deuterated Dihydrothymine; [2,4-13C2, 5,6,6-2H3]-5-Methyluracil (related); Isotopically Labeled Thymine; 5-Methyluracil-d6 (dihydro); NMR Standard Thymine-d6
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro Thymine-D6 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.