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1,5-Difluoro-2-Iodo-4-Methyl-Benzene CAS NO 333447-42-0


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CAS No.:333447-42-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,5-Difluoro-2-Iodo-4-Methyl-Benzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and iodine atoms, which enable precise functionalization and arene activation for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorine-containing drug candidates.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated aromatic structures.
  • Material Science: Building block for creating specialized polymers, liquid crystals, and organic electronic materials.
  • Cross-Coupling Reactions: Serves as an excellent substrate in palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the reactive iodine moiety.
  • Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries in medicinal chemistry.
  • Fluorine Chemistry: Integral in the study and application of fluorination techniques and the development of fluorinated aromatic compounds.

Basic Information

Product Name 1,5-Difluoro-2-Iodo-4-Methyl-Benzene
CAS No. 333447-42-0
Molecular Formula C7H5F2I
Molecular Weight 253.02 g/mol
Synonyms 2-Iodo-1,5-difluoro-4-methylbenzene; 4-Methyl-2,6-difluoroiodobenzene; 1,5-Difluoro-2-iodo-p-xylene; 2,6-Difluoro-4-iodotoluene; 4-Iodo-3,5-difluorotoluene; Benzene, 1,5-difluoro-2-iodo-4-methyl-; DFIMB
EINECS Contact for details

Quality Control

Our 1,5-Difluoro-2-Iodo-4-Methyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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