Description

5-(Trifluoromethyl)-1-Phenyl-1H-Pyrazole is a high-value fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl group attached to a phenylpyrazole core, provides unique electronic and steric properties essential for developing novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated characteristics.
• Chemical Biology: Acts as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects requiring complex, fluorinated heterocyclic structures.

Basic Information

Product Name	5-(Trifluoromethyl)-1-Phenyl-1H-Pyrazole
CAS No.	333363-79-4
Molecular Formula	C10H7F3N2
Molecular Weight	212.18 g/mol
Synonyms	1-Phenyl-5-(trifluoromethyl)-1H-pyrazole; 5-(Trifluoromethyl)-1-phenylpyrazole; 1-Phenyl-5-(trifluoromethyl)pyrazole; 5-Trifluoromethyl-1-phenyl-1H-pyrazole; 333363-79-4; 1H-Pyrazole, 5-(trifluoromethyl)-1-phenyl-; 1-Phenyl-5-trifluoromethylpyrazole
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1-Phenyl-1H-Pyrazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.