Description

(3-Trifluoromethyl-5,6-Dihydro-4H-Cyclopenta-Pyrazol-1-Yl)-Acetic Acid is a high-value, functionalized heterocyclic building block featuring a cyclopentane-fused pyrazole core with a trifluoromethyl group and an acetic acid side chain. This compound is specifically engineered to serve as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical agents, where its unique structure imparts desirable metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in therapeutic areas targeting inflammation, central nervous system (CNS) disorders, and oncology.
• Agrochemical Research: Used in the synthesis of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for advanced functional materials, including liquid crystals and organic semiconductors, due to its rigid, fluorinated structure.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	(3-Trifluoromethyl-5,6-Dihydro-4H-Cyclopenta-Pyrazol-1-Yl)-Acetic Acid
CAS No.	333309-24-3
Molecular Formula	C9H9F3N2O2
Molecular Weight	234.18 g/mol
Synonyms	2-(3-(Trifluoromethyl)-5,6-dihydro-4H-cyclopenta[c]pyrazol-1-yl)acetic acid; 1-Carboxymethyl-3-trifluoromethyl-4,5,6,7-tetrahydroindazole; (3-Trifluoromethyl-4,5,6,7-tetrahydro-1H-indazol-1-yl)acetic acid; TFMPA-CP; CP-Pyrazole acetic acid derivative; 333309-24-3; 3-Trifluoromethyl-1,4,5,6-tetrahydrocyclopentapyrazole-1-acetic acid
EINECS	Contact for details

Quality Control

Every batch of (3-Trifluoromethyl-5,6-Dihydro-4H-Cyclopenta-Pyrazol-1-Yl)-Acetic Acid is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards for advanced pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to guarantee supply chain transparency and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.