Description

1-[4-(Diethylamino)-2-Hydroxyphenyl]-2,2,2-Trifluoro-1-Ethanone is a specialized trifluoromethyl ketone derivative featuring a diethylamino-substituted hydroxyphenyl group, making it a valuable intermediate for advanced organic synthesis. Its molecular structure is engineered to serve as a key building block in the development of high-performance materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with unique optical or electronic properties.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an electron-transport or host material precursor in the manufacture of advanced OLED displays and lighting systems.
• Chemical Research & Development: Employed as a standard or reagent in methodological studies for new fluorination techniques or asymmetric synthesis pathways in academic and industrial R&D labs.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes, pigments, and photoinitiators due to its conjugated system and light-absorbing characteristics.

Basic Information

Product Name	1-[4-(Diethylamino)-2-Hydroxyphenyl]-2,2,2-Trifluoro-1-Ethanone
CAS No.	333303-11-0
Molecular Formula	C₁₂H₁₄F₃NO₂
Molecular Weight	261.24 g/mol
Synonyms	2,2,2-Trifluoro-1-[4-(diethylamino)-2-hydroxyphenyl]ethanone; 4-(Diethylamino)-2-hydroxy-α,α,α-trifluoroacetophenone; 1-(4-Diethylamino-2-hydroxyphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-diethylamino-2-hydroxyphenyl)ethan-1-one; N,N-Diethyl-4-(2,2,2-trifluoroacetyl)-3-hydroxyaniline; 4-Diethylamino-2-hydroxy-α,α,α-trifluoroacetophenone; TFK-DEAH (abbreviation)
EINECS	Contact for details

Quality Control

Our 1-[4-(Diethylamino)-2-Hydroxyphenyl]-2,2,2-Trifluoro-1-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance assurance for your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.