Description

5-[(1,3-Dioxoisoindol-2-Yl)Methyl]Thiophene-2-Sulfonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile intermediate for constructing complex molecules with potential biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel sulfonamide derivatives and heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the thiophene-sulfonyl chloride moiety.
• Material Science: Intermediate for creating specialized polymers, ligands, or functional materials with specific electronic or binding properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling biomolecules, or developing activity-based probes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring this precise molecular scaffold.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	5-[(1,3-Dioxoisoindol-2-Yl)Methyl]Thiophene-2-Sulfonyl Chloride
CAS No.	332361-07-6
Molecular Formula	C13H8ClNO4S2
Molecular Weight	341.79 g/mol
Synonyms	2-[(5-Chlorosulfonylthiophen-2-yl)methyl]isoindole-1,3-dione; N-(5-Chlorosulfonyl-2-thienylmethyl)phthalimide; 5-(Phthalimidomethyl)thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-; 5-(1,3-Dioxoisoindolin-2-ylmethyl)thiophene-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-[(1,3-Dioxoisoindol-2-Yl)Methyl]Thiophene-2-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your synthetic workflows. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.