Description

Benzenesulfonyl Chloride, 3-Nitro-4-(2-Oxo-1-Pyrrolidinyl) is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a reactive sulfonyl chloride group and a nitro-substituted pyrrolidinone moiety, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring sulfonamide-based structures.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the sulfonyl chloride group enables the introduction of specific bioactive moieties.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism, leveraging its electrophilic sulfonyl chloride group.
• Dye and Pigment Synthesis: Intermediate for creating complex, color-fast azo dyes or specialty pigments requiring sulfonated aromatic backbones.

Basic Information

Product Name	Benzenesulfonyl Chloride, 3-Nitro-4-(2-Oxo-1-Pyrrolidinyl)
CAS No.	331256-60-1
Molecular Formula	C10H9N2O5SCl
Molecular Weight	304.71 g/mol
Synonyms	3-Nitro-4-(2-oxopyrrolidin-1-yl)benzenesulfonyl chloride; 1-(4-Chlorosulfonyl-2-nitrophenyl)pyrrolidin-2-one; 4-(2-Oxo-1-pyrrolidinyl)-3-nitrobenzenesulfonyl chloride; 2-Pyrrolidinone, 1-[4-(chlorosulfonyl)-2-nitrophenyl]-; 3-Nitro-4-(2-oxo-1-pyrrolidinyl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Benzenesulfonyl Chloride, 3-Nitro-4-(2-Oxo-1-Pyrrolidinyl) is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.