Description

Pdk1/Akt/Flt Dual Pathway Inhibitor CAS NO 331253-86-2 is a potent and selective small molecule inhibitor designed for advanced biochemical and pharmacological research. This compound is critical for studying cellular signaling networks, particularly those involving cell survival, proliferation, and angiogenesis. It is an essential research tool for pharmaceutical developers, academic institutions, and biotechnology companies focused on oncology, metabolic disorders, and neurodegenerative disease research.

Application

• Biochemical Research: Used as a key reagent to inhibit the PDK1/AKT and FLT3 signaling pathways in in vitro cell-based assays.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in high-throughput screening and lead optimization for cancer therapeutics.
• Mechanistic Studies: Enables the investigation of crosstalk between the PI3K/PDK1/AKT and receptor tyrosine kinase (RTK) pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies on apoptosis, cell cycle regulation, and tumor biology.
• Preclinical Evaluation: Applied in animal model studies to assess the efficacy and pharmacokinetics of pathway-targeted therapeutic strategies.

Basic Information

Product Name	Pdk1/Akt/Flt Dual Pathway Inhibitor
CAS No.	331253-86-2
Molecular Formula	C₂₁H₂₁N₇O₂S
Molecular Weight	435.51 g/mol
Synonyms	OSU-03012; AR-12; 5-[4-(4-Methyl-1-piperazinyl)phenyl]amino]-4-(trifluoromethyl)-2(1H)-pyrimidinone; PDK1/AKT Inhibitor; PDK1/Akt/Flt3 Inhibitor; Akt/PDK1 Signaling Inhibitor; AR12; UNC-OSU-03012
EINECS	Contact for details

Quality Control

Every batch of our Pdk1/Akt/Flt Dual Pathway Inhibitor is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our stringent in-house specifications for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.