Description

8-Iso Prostaglandin E2 Isopropyl Ester is a synthetic isoprostane analog, a potent and stable derivative of prostaglandin E2. This compound is valued for its role as a key biochemical tool in pharmacological and biomedical research, particularly in studying oxidative stress and inflammatory pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity reference standards and intermediates for drug discovery and diagnostic applications.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the quantification and validation of isoprostanes in biological samples via LC-MS/MS or ELISA.
• Pharmacological Studies: Serves as a potent agonist or tool compound for investigating prostaglandin receptor (EP) signaling and related inflammatory responses in cell-based assays.
• Oxidative Stress Biomarker: Employed in the development and calibration of diagnostic assays to measure lipid peroxidation and oxidative damage in clinical research.
• Drug Discovery Intermediates: Acts as a critical synthetic intermediate or building block in the development of novel anti-inflammatory or cardiovascular therapeutic agents.
• Academic & Institutional Research: Provides a reliable reagent for universities and research institutes studying eicosanoid biology, signal transduction, and disease mechanisms.

Basic Information

Product Name	8-Iso Prostaglandin E2 Isopropyl Ester
CAS No.	330589-21-4
Molecular Formula	C23H38O5
Molecular Weight	394.55 g/mol
Synonyms	8-iso-PGE2 Isopropyl Ester; 8-Epi-prostaglandin E2 Isopropyl Ester; 15(S)-8-iso-PGE2 Isopropyl Ester; 8-Isoprostane E2 Isopropyl Ester; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxy-4-(1-methylethoxy)-1-buten-1-yl]-5-oxocyclopentyl]-5-heptenoic Acid Isopropyl Ester; 15(S)-8-iso-Prostaglandin E2 Isopropyl Ester; 8-iso Prostaglandin E2 i-Pr Ester
EINECS	Contact for details

Quality Control

Our 8-Iso Prostaglandin E2 Isopropyl Ester is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by advanced analytical techniques including HPLC and NMR. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.