Description

Gp91 Ds-Tat CAS NO 329902-61-6 is a cell-permeable peptide inhibitor specifically designed to target the NADPH oxidase complex, a key generator of reactive oxygen species (ROS) in biological systems. This compound is critical for researchers and developers investigating oxidative stress pathways, inflammatory responses, and related disease mechanisms. It is primarily utilized in advanced life science research, pharmaceutical development, and as a biochemical tool for probing intracellular signaling.

Application

• Biomedical Research: A vital tool for studying the role of NADPH oxidase (NOX2) in cellular models of inflammation, cardiovascular disease, and neurodegenerative disorders.
• Drug Discovery & Development: Used in target validation and screening assays to identify novel therapeutics aimed at modulating oxidative stress.
• Signal Transduction Studies: Employed to dissect ROS-dependent signaling pathways and their impact on gene expression, apoptosis, and cell proliferation.
• Academic & Institutional Research: Essential for basic science investigations into immune cell activation, phagocytosis, and host defense mechanisms.
• Preclinical Studies: Supports in vitro and ex vivo research to understand disease etiology and evaluate potential intervention strategies.

Basic Information

Product Name	Gp91 Ds-Tat
CAS No.	329902-61-6
Molecular Formula	C92H146N32O22S
Molecular Weight	2044.4 g/mol
Synonyms	gp91ds-tat; NOX2ds-tat; gp91phox inhibitory peptide; NADPH oxidase inhibitory peptide; gp91phox docking sequence peptide; Cytochrome b-245 heavy chain inhibitor; Tat-gp91ds; H-RKKRRQRRR-CSTRIRRQL-NH2; (Arg)9-CSTRIRRQL-amide
EINECS	Contact for details

Quality Control

Our Gp91 Ds-Tat is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.