Description

1H-Purine-2,6-Dione, 7-[(4-Chlorophenyl)Methyl]-3,7-Dihydro-3-Methyl-8-[(1-Methylethyl)Thio]- is a specialized purine derivative with a unique thiomethyl-substituted structure, making it a valuable pharmaceutical intermediate and research chemical. Its molecular design offers a critical scaffold for the synthesis of novel compounds targeting specific biological pathways. This high-purity intermediate is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams requiring precise and reliable building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for therapeutic areas involving purine-based molecules.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and biochemical assays to investigate purine metabolism and related cellular processes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for agrochemical, material science, or specialty chemical applications.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1H-Purine-2,6-Dione, 7-[(4-Chlorophenyl)Methyl]-3,7-Dihydro-3-Methyl-8-[(1-Methylethyl)Thio]-
CAS No.	326919-27-1
Molecular Formula	C16H17ClN4OS
Molecular Weight	348.85 g/mol
Synonyms	7-[(4-Chlorophenyl)methyl]-3,7-dihydro-3-methyl-8-(propan-2-ylsulfanyl)-1H-purine-2,6-dione; 8-(Isopropylthio)-7-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 7-(4-Chlorobenzyl)-8-(isopropylthio)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-(Isopropylthio)-3-methyl-7-(4-chlorobenzyl)xanthine; 7-(p-Chlorobenzyl)-8-(isopropylthio)-3-methylxanthine; 3-Methyl-7-(4-chlorobenzyl)-8-(isopropylthio)xanthine; Purine derivative 326919-27-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.