Description

Benzene, 1-Fluoro-4-[(1R)-1-Methylpropyl]- (9Ci) is a specialized fluorinated aromatic compound, identified by CAS number 326879-17-8, serving as a valuable chiral building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom and a chiral sec-butyl group, makes it a critical intermediate for constructing complex molecules with specific stereochemistry. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorinated aromatic core and chiral center enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Catalyst & Ligand Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced thermal, chemical, or optical properties.
• Chemical Research & Development: A versatile reagent for method development and exploration of new fluorination and cross-coupling reactions in academic and industrial R&D labs.

Basic Information

Product Name	Benzene, 1-Fluoro-4-[(1R)-1-Methylpropyl]- (9Ci)
CAS No.	326879-17-8
Molecular Formula	C11H15F
Molecular Weight	166.24 g/mol
Synonyms	1-Fluoro-4-[(1R)-1-methylpropyl]benzene; (R)-1-Fluoro-4-sec-butylbenzene; (R)-4-sec-Butylfluorobenzene; (R)-1-sec-Butyl-4-fluorobenzene; p-[(1R)-1-Methylpropyl]fluorobenzene; (R)-p-sec-Butylfluorobenzene; Benzene, 1-fluoro-4-[(1R)-1-methylpropyl]-; 326879-17-8
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1-Fluoro-4-[(1R)-1-Methylpropyl]- (9Ci) is produced under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the stringent requirements of process chemistry and R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.