Description

2,6-Dibromo-3,5-Difluoroisonicotinic Acid is a high-value, multi-halogenated pyridine derivative that serves as a critical synthetic intermediate. Its unique structure, featuring bromine and fluorine substituents on the pyridine ring, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-infective properties.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used to create novel ligands for transition metal catalysts in cross-coupling and other organic transformations.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	2,6-Dibromo-3,5-Difluoroisonicotinic Acid
CAS No.	325461-60-7
Molecular Formula	C6HBr2F2NO2
Molecular Weight	315.88 g/mol
Synonyms	3,5-Difluoro-2,6-dibromopyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2,6-dibromo-3,5-difluoro-; 2,6-Dibromo-3,5-difluoropyridine-4-carboxylic Acid; 2,6-Dibromo-3,5-difluoro-4-pyridinecarboxylic Acid; 325461-60-7; DBDFIA
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-3,5-Difluoroisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.