Description

tert-Butyl (6-(Trifluoromethyl)Pyridin-3-Yl)Carbamate is a high-value, protected amine intermediate featuring a pyridine core substituted with a trifluoromethyl group. This compound is critical for its role in facilitating the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its unique electronic properties imparted by the fluorine atoms.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	tert-Butyl (6-(Trifluoromethyl)Pyridin-3-Yl)Carbamate
CAS No.	325457-86-1
Molecular Formula	C11H13F3N2O2
Molecular Weight	262.23 g/mol
Synonyms	Boc-6-(Trifluoromethyl)pyridin-3-amine; tert-Butyl N-[6-(trifluoromethyl)pyridin-3-yl]carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-(trifluoromethyl)pyridine; 5-Amino-2-(trifluoromethyl)pyridine tert-butylcarbamate; 6-(Trifluoromethyl)pyridin-3-amine, N-Boc-protected; Boc-5-Amino-2-trifluoromethylpyridine; N-Boc-5-Amino-2-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-(Trifluoromethyl)Pyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.