Description

5-(1,3-Oxazol-5-Yl)-2-Thiophenesulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonyl functional group, which is pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for sulfonamide-based therapeutics targeting various diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the sulfonyl moiety enhances activity and selectivity.
• Material Science: Employed in the creation of functional polymers and advanced organic electronic materials due to its reactive sulfonyl chloride group.
• Chemical Biology: Acts as a versatile reagent for bioconjugation and probe synthesis, facilitating the study of biological processes.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	5-(1,3-Oxazol-5-Yl)-2-Thiophenesulfonyl Chloride
CAS No.	321309-40-4
Molecular Formula	C7H4ClNO3S2
Molecular Weight	249.69 g/mol
Synonyms	5-(Oxazol-5-yl)thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-(5-oxazolyl)-; 5-(1,3-Oxazol-5-yl)thiophene-2-sulfonyl chloride; 5-(Oxazol-5-yl)-2-thienylsulfonyl chloride; 5-(1,3-Oxazol-5-yl)-2-thiophenesulfonylchloride; 5-(Oxazol-5-yl)thiophene-2-sulphonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(1,3-Oxazol-5-Yl)-2-Thiophenesulfonyl Chloride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.