Description

3,4-Dihydro-2H-1,5-Benzodioxepine-7-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the sulfonamide functional group, enabling the creation of molecules with tailored biological and physical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the sulfonyl group enhances activity and selectivity.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and functional materials that incorporate sulfonamide linkages for improved stability or performance.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation and the development of chemical probes to study enzyme activity and protein function.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3,4-Dihydro-2H-1,5-Benzodioxepine-7-Sulfonyl Chloride
CAS No.	321309-38-0
Molecular Formula	C9H9ClO4S
Molecular Weight	248.68 g/mol
Synonyms	7-Chlorosulfonyl-3,4-dihydro-2H-1,5-benzodioxepine; 1,5-Benzodioxepine-7-sulfonyl chloride, 3,4-dihydro-2H-; 2H-1,5-Benzodioxepine-7-sulfonyl chloride, 3,4-dihydro-; 3,4-Dihydro-2H-benzo[b][1,5]dioxepine-7-sulfonyl chloride; 7-(Chlorosulfonyl)-3,4-dihydro-2H-1,5-benzodioxepine
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-1,5-Benzodioxepine-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.