Description

5-Methyl-4-Isoxazolesulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the 5-methyl-4-isoxazolesulfonyl moiety, a key functional group for modulating the biological activity and physicochemical properties of target molecules. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the isoxazole ring contributes to efficacy.
• Chemical Biology Probes: Serves as a reactive handle for labeling proteins or modifying biomolecules in proteomics and biochemical research.
• Material Science Research: Employed in the synthesis of specialized polymers or functional materials that require sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-Methyl-4-Isoxazolesulfonyl Chloride
CAS No.	321309-26-6
Molecular Formula	C4H4ClNO3S
Molecular Weight	181.60 g/mol
Synonyms	4-Isoxazolesulfonyl chloride, 5-methyl-; 5-Methylisoxazole-4-sulfonyl chloride; 5-Methyl-1,2-oxazole-4-sulfonyl chloride; 321309-26-6; 5-Methyl-4-isoxazolesulfonylchloride
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-4-Isoxazolesulfonyl Chloride is manufactured and tested under strict quality management systems to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.