Description

3-Fluoro-4-(trifluoromethyl)benzenecarbothioamide is a high-value fluorinated aromatic building block and a key intermediate in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines fluorine and trifluoromethyl substituents with a reactive thioamide group, enabling precise modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced materials with specific optical or electronic properties.
• Ligand Synthesis: The thioamide moiety can be utilized to develop novel chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Fluoro-4-(trifluoromethyl)benzenecarbothioamide
CAS No.	317319-16-7
Molecular Formula	C8H5F4NS
Molecular Weight	223.19 g/mol
Synonyms	3-Fluoro-4-(trifluoromethyl)benzothioamide; 4-(Trifluoromethyl)-3-fluorobenzenecarbothioamide; 3-Fluoro-α,α,α-trifluoro-p-toluothioamide; 3-Fluoro-4-trifluoromethylthiobenzamide; Benzenecarbothioamide, 3-fluoro-4-(trifluoromethyl)-; 3-Fluoro-4-trifluoromethylbenzothioamide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(trifluoromethyl)benzenecarbothioamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.