Description

Gw0742 is a high-purity, synthetic small molecule compound with the CAS number 317318-84-6. This compound is of significant interest in pharmaceutical and biochemical research due to its role as a potent and selective agonist for the peroxisome proliferator-activated receptor delta (PPARδ). It is primarily utilized by research institutions and pharmaceutical development companies engaged in metabolic disease research, inflammation studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of PPARδ-targeted therapies.
• Metabolic Disease Studies: Used in preclinical research to investigate its effects on lipid metabolism, glucose homeostasis, and energy expenditure for conditions like dyslipidemia and type 2 diabetes.
• Inflammation and Immunology Research: Applied in cellular and animal models to study the modulation of inflammatory pathways and immune responses.
• Biochemical Assay Development: Employed as a critical ligand in high-throughput screening (HTS) and binding assays to identify and characterize new PPARδ modulators.
• Academic Research: Utilized in university and institutional labs for fundamental research into nuclear receptor biology and signal transduction mechanisms.
• Contract Manufacturing: Supplied as a building block for the custom synthesis of more complex molecules in medicinal chemistry programs.

Basic Information

Product Name	Gw0742
CAS No.	317318-84-6
Molecular Formula	C21H20F3NO4S2
Molecular Weight	471.51 g/mol
Synonyms	GW-0742; GW0742; 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid; PPARδ Agonist GW0742; GSK-3787; BMS-687453; PPAR Delta Agonist
EINECS	Contact for details

Quality Control

Every batch of Gw0742 (CAS 317318-84-6) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.