Description

3-Nitro-4-(trifluoromethoxy)benzaldehyde is a high-purity aromatic aldehyde building block featuring both nitro and trifluoromethoxy functional groups. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of key pharmacophores and structural motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, where its electronic properties are beneficial.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Nitro-4-(trifluoromethoxy)benzaldehyde
CAS No.	315188-37-5
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	4-(Trifluoromethoxy)-3-nitrobenzaldehyde; 3-Nitro-4-trifluoromethoxybenzaldehyde; Benzaldehyde, 3-nitro-4-(trifluoromethoxy)-; 3-Nitro-α,α,α-trifluoro-p-anisaldehyde
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(trifluoromethoxy)benzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.