Description

2-Chloromethyl-6-Fluoropyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloromethyl and fluoro substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is particularly valuable for pharmaceutical research and agrochemical development, where it is used to introduce key functional groups and modulate biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the fluoropyridine moiety contributes to efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science applications.
• Functional Material Development: Employed in the research and production of advanced materials, including liquid crystals and organic electronic components.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemistry and process research, enabling further functionalization through nucleophilic substitution and cross-coupling reactions.

Basic Information

Product Name	2-Chloromethyl-6-Fluoropyridine
CAS No.	315180-16-6
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	6-Fluoro-2-(chloromethyl)pyridine; 2-(Chloromethyl)-6-fluoropyridine; (6-Fluoropyridin-2-yl)methyl chloride; 6-Fluoro-2-pyridinemethyl chloride; 2-Chloromethyl-6-fluoropyridine; 315180-16-6; 6-Fluoro-2-chloromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-6-Fluoropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.