Description

D-[2-13C]Galactose is a stable isotope-labeled analog of the monosaccharide galactose, specifically enriched with carbon-13 at the C-2 position. This precise labeling is critical for advanced metabolic research, enabling scientists to accurately trace and quantify galactose metabolism and related biochemical pathways using techniques like NMR spectroscopy and mass spectrometry. It is an essential tool for researchers and developers in the pharmaceutical, diagnostic, and life science sectors, particularly for studies in carbohydrate metabolism, inborn errors of metabolism, and the development of novel diagnostic tracers.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study the dynamics of galactose metabolism in cell cultures, tissues, and whole organisms.
• Clinical Research & Diagnostics: Serves as a key component in developing and calibrating diagnostic assays for disorders like Galactosemia.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to investigate the fate of carbohydrate-based therapeutics.
• NMR Spectroscopy: Acts as an internal standard or probe for structural and dynamic studies of carbohydrate-protein interactions.
• Mass Spectrometry (MS): Provides a distinct mass signature for the sensitive and specific detection of galactose-derived metabolites in complex biological samples.
• Biochemical Pathway Elucidation: Helps in mapping and validating specific enzymatic steps within the Leloir pathway and related metabolic networks.

Basic Information

Product Name	D-[2-13C]Galactose
CAS No.	314062-47-0
Molecular Formula	C512C13H12O6
Molecular Weight	181.15 g/mol (for 13C1 isotopologue)
Synonyms	D-Galactose-2-13C; (2-13C)Galactose; Galactose-2-13C; 13C Labeled D-Galactose; [2-13C]-D-Galactopyranose; D-(+)-Galactose-2-13C; 2-13C Isotope of D-Galactose; Stable Isotope-Labeled Galactose
EINECS	Contact for details

Quality Control

Every batch of D-[2-13C]Galactose is manufactured and tested under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data from NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, specifying the isotopic enrichment, chemical purity, and absence of critical impurities. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Complies
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+80.0° to +81.5° (c=10, H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.