Description

1-Acetylindoline-6-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the sulfonyl moiety is a common pharmacophore.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized for labeling proteins or other biomolecules to study biological pathways and interactions.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic compounds and other sophisticated molecular architectures in research laboratories.

Basic Information

Item	Details
Product Name	1-Acetylindoline-6-Sulfonyl Chloride
CAS No.	313690-18-5
Molecular Formula	C10H10ClNO3S
Molecular Weight	259.71 g/mol
Synonyms	6-(Chlorosulfonyl)-1-acetylindoline; 1-Acetyl-6-indolinesulfonyl chloride; 1-Acetylindoline-6-sulfonyl chloride; N-Acetyl-2,3-dihydro-1H-indole-6-sulfonyl chloride; 2,3-Dihydro-1-acetyl-1H-indole-6-sulfonyl chloride; 1H-Indole-6-sulfonyl chloride, 2,3-dihydro-1-acetyl-; 313690-18-5
EINECS	Contact for details

Quality Control

Our 1-Acetylindoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.