Description

Glutaminase C-In-1 CAS NO 311795-38-7 is a potent and selective small molecule inhibitor of the enzyme glutaminase C (GAC), a key target in cancer metabolism research. This compound matters for its ability to specifically block glutamine metabolism in tumor cells, a process critical for their growth and survival. It is primarily needed by researchers in pharmaceutical R&D, oncology, and metabolic disease studies for investigating novel therapeutic pathways and validating drug targets.

Application

• Cancer Metabolism Research: Used as a tool compound to study the role of glutaminase in tumor cell proliferation, survival, and bioenergetics.
• Oncology Drug Discovery: Serves as a reference standard and lead compound for developing novel glutaminase C inhibitors for cancer therapy.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in vitro enzymatic assays to identify and characterize new inhibitors.
• Mechanistic Studies: Facilitates research into glutamine-dependent signaling pathways and their connection to oncogenesis.
• Preclinical Research: Used in cell culture and animal models to evaluate the therapeutic potential of targeting glutaminase.

Basic Information

Product Name	Glutaminase C-In-1
CAS No.	311795-38-7
Molecular Formula	C₁₉H₂₀N₄O₃
Molecular Weight	352.39 g/mol
Synonyms	BPTES analog; Glutaminase C Inhibitor-1; GAC Inhibitor-1; N,N'-(1,4-Phenylenedicarbonyl)bis(2-phenylacetamide); 5-Phenyl-N,N'-(terephthaloylbis(azanediyl))bis(1H-pyrazole-3-carboxamide); CB-839 related compound; Glutaminase inhibitor BPTES derivative
EINECS	Contact for details

Quality Control

Our Glutaminase C-In-1 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods, to ensure consistency and reliability for research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.