Description

Talmapimod Hcl is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the development of novel therapeutic agents targeting specific kinase pathways. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions engaged in drug discovery and preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in kinase inhibition studies and signal transduction pathway analysis.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and lead optimization processes for novel drug candidates.
• Preclinical Studies: Utilized in in vitro and in vivo models to investigate pharmacokinetics, pharmacodynamics, and efficacy.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.

Basic Information

Product Name	Talmapimod Hcl
CAS No.	309915-12-6
Molecular Formula	C₂₀H₂₀N₄O₃S • HCl
Molecular Weight	432.92 g/mol
Synonyms	Talmapimod Hydrochloride; 5-[(5-Fluoro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]-2-methylbenzenesulfonamide hydrochloride; SC-10; SC 10; SC10; p38 MAP Kinase Inhibitor (Talmapimod); BIRB 796 Derivative
EINECS	Contact for details

Quality Control

Our Talmapimod Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed HPLC/LC-MS data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.