Description

Inauhzin is a potent and selective small molecule inhibitor of SIRT1, a key enzyme involved in cellular stress response and aging pathways. This compound is a critical research tool for studying the role of sirtuins in oncology, neurology, and metabolic diseases. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on epigenetic regulation and targeted therapy development.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate for developing novel therapeutics targeting SIRT1-related pathways.
• Oncology Research: Used in in vitro and in vivo studies to investigate the role of SIRT1 in tumor suppression, cell senescence, and cancer cell proliferation.
• Neurodegenerative Disease Studies: Employed in research models for Alzheimer's, Parkinson's, and other neurological conditions to explore SIRT1's neuroprotective effects.
• Metabolic Disorder Investigation: Applied in studies of diabetes, obesity, and aging to understand metabolic regulation via sirtuin activity.
• Epigenetics and Cell Biology: Serves as a precise chemical probe to modulate histone deacetylation and study downstream gene expression effects.
• Biomarker Discovery: Facilitates the identification and validation of novel biomarkers associated with SIRT1 inhibition in various disease states.

Basic Information

Product Name	Inauhzin
CAS No.	309271-94-1
Molecular Formula	C₁₉H₁₈N₄O₂
Molecular Weight	334.37 g/mol
Synonyms	INZ; INZ-1; Inauhzin (INZ); 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; SIRT1 Inhibitor IV; Sirtuin 1 Inhibitor, Inauhzin; 6-Chloro-1,2,3,4-tetrahydro-9H-carbazole-1-carboxamide
EINECS	Contact for details

Quality Control

Our Inauhzin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.