Description

Cox-1 Inhibitor Ii CAS NO 304913-22-2 is a potent and selective small molecule inhibitor of the cyclooxygenase-1 (COX-1) enzyme. This compound is a critical research tool for investigating the distinct physiological and pathological roles of COX-1 versus COX-2 in inflammation, pain, and cellular signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and basic biochemical research.

Application

• Pharmacological Research: Used as a reference standard and active probe to study the specific functions of the COX-1 isoenzyme in vitro and in vivo.
• Drug Discovery Programs: Serves as a key compound for screening, validating assays, and developing new anti-inflammatory or analgesic agents with improved selectivity profiles.
• Biochemical Mechanism Studies: Employed to elucidate the downstream effects of COX-1 inhibition on prostaglandin synthesis, platelet aggregation, and gastrointestinal cytoprotection.
• Academic & Institutional Research: A fundamental tool for university labs and research institutes exploring inflammation pathways, cancer biology, and neurobiology where COX-1 is implicated.
• Target Validation: Critical for confirming COX-1 as a therapeutic target in specific disease models before committing to extensive development campaigns.

Basic Information

Product Name	Cox-1 Inhibitor Ii
CAS No.	304913-22-2
Molecular Formula	C17H14F3NO3S
Molecular Weight	369.36 g/mol
Synonyms	SC-560; 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole; COX-1 Inhibitor II; SC560; Selective COX-1 Inhibitor SC-560; 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole
EINECS	Contact for details

Quality Control

Our Cox-1 Inhibitor Ii is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, batch-to-batch consistency, and reliable performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.