Description

Sirt2 Inhibitor, Inactive Control, Agk7 is a high-purity chemical compound designed for use as a critical control in biochemical and pharmacological research. This compound serves as an essential negative control in studies targeting Sirtuin 2 (Sirt2) deacetylase activity, allowing researchers to validate the specificity of active inhibitors and ensure experimental accuracy. It is primarily utilized by scientists and R&D teams in the pharmaceutical, biotechnology, and academic sectors for target validation, assay development, and mechanistic studies in areas such as neurodegeneration, cancer, and metabolic disorders.

Application

• Critical negative control in Sirt2-specific inhibitor screening assays and high-throughput screening (HTS) campaigns.
• Validation of assay specificity and confirmation of on-target effects in cell-based and biochemical studies of Sirtuin biology.
• Essential tool compound for research in neurodegenerative diseases (e.g., Parkinson's, Alzheimer's) where Sirt2 is a therapeutic target.
• Use in oncology research to differentiate Sirt2-mediated effects from off-target activities in cancer cell models.
• Pharmacological studies requiring a structurally similar but inactive analog to establish baseline activity and compound selectivity.
• Academic and industrial R&D for probing the role of Sirt2 in aging, metabolism, and other physiological processes.

Basic Information

Product Name	Sirt2 Inhibitor, Inactive Control, Agk7
CAS No.	304896-21-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AGK7; AGK 7; Sirt2 Inactive Control; Sirtuin 2 Inhibitor Inactive Control; (E)-N-(3-(3-(Dimethylamino)propylamino)-4-methoxyphenyl)-3-phenylacrylamide; Inactive analog of Sirt2 inhibitor; Negative Control for Sirt2 studies
EINECS	Contact for details

Quality Control

Our Sirt2 Inhibitor, Inactive Control, Agk7 is manufactured under strict quality protocols to ensure the high purity and batch-to-batch consistency required for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and analytical data is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.