Description

(3,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active pharmaceutical ingredients (APIs) and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and novel drug candidates, especially in oncology and CNS research.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the palladium-catalyzed formation of biaryl and other C-C bonds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and sensors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	(3,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid
CAS No.	304876-33-3
Molecular Formula	C10H12BNO3
Molecular Weight	205.02 g/mol
Synonyms	5-Borono-3,3-dimethyl-1,3-dihydro-2H-indol-2-one; 3,3-Dimethyl-2-oxoindoline-5-boronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3-dimethylindolin-2-one (Pinacol ester precursor); 3,3-Dimethyloxindole-5-boronic acid; 5-Boron-3,3-dimethyl-2-oxindole; (3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)boronic acid; 5-Borono-3,3-dimethyloxindole
EINECS	Contact for details

Quality Control

Every batch of (3,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions and pharmaceutical R&D. A detailed Certificate of Analysis (COA) specifying purity (typically by HPLC/NMR), identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.