Description

n-[[trans-4-[(4,5-Dihydro[1]Benzothiepino[5,4-D]Thiazol-2-Yl)Amino]Cyclohexyl]Methyl]Methanesulfonamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, small-molecule therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing new drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Synthesis: Employed in the development pathway for potential anticancer agents targeting specific cellular pathways.
• Kinase Inhibitor Development: Its structural motifs make it relevant for creating compounds that modulate kinase activity, a common target in modern therapeutics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	n-[[trans-4-[(4,5-Dihydro[1]Benzothiepino[5,4-D]Thiazol-2-Yl)Amino]Cyclohexyl]Methyl]Methanesulfonamide
CAS No.	304008-29-5
Molecular Formula	C20H25N3O2S2
Molecular Weight	403.56 g/mol
Synonyms	trans-N-[[4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]methanesulfonamide; Methanesulfonamide, N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-; UNII-8J3Z5M55W2; 8J3Z5M55W2; BDBM50191057; AOB67717; CHEMBL3185222; ZINC000003869923
EINECS	Contact for details

Quality Control

Our n-[[trans-4-[(4,5-Dihydro[1]Benzothiepino[5,4-D]Thiazol-2-Yl)Amino]Cyclohexyl]Methyl]Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.