Description

Tak-715 is a potent and selective inhibitor of the c-Jun N-terminal kinase (JNK) signaling pathway, a key target in cellular stress response and inflammation. This compound is crucial for research and development in the pharmaceutical and biotechnology sectors, offering a valuable tool for studying apoptosis, inflammation, and neurodegenerative diseases. It is primarily utilized by researchers in drug discovery, academic institutions, and contract research organizations (CROs) focused on developing novel therapeutics for conditions like Parkinson's disease, stroke, and diabetes.

Application

• Biochemical Research: A critical tool for studying the JNK signaling pathway's role in cellular processes.
• Drug Discovery & Development: Used as a reference standard and lead compound in developing anti-inflammatory and neuroprotective agents.
• Neurodegenerative Disease Research: Investigated in models of Parkinson's disease, Alzheimer's disease, and ischemic stroke for its neuroprotective effects.
• Inflammation & Immunology Studies: Applied in research to understand and modulate inflammatory responses in various disease models.
• Apoptosis (Programmed Cell Death) Research: Utilized to elucidate mechanisms of cell death and survival in cancer and other pathologies.
• Academic & Preclinical Studies: Serves as a key reagent in university and institutional labs for fundamental biological research.

Basic Information

Product Name	Tak-715
CAS No.	303162-79-0
Molecular Formula	C₁₇H₁₄N₄O₂S
Molecular Weight	338.38 g/mol
Synonyms	N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide; BENTA; 3-Cyano-N-(1-naphthoyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-amine; JNK Inhibitor IX; JNK Inhibitor Tak-715; TAK-715; (2-((1-Naphthoyl)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile)
EINECS	Contact for details

Quality Control

Our Tak-715 is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in your experimental workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.