Description

Pyridine, 2,4-Difluoro-, 1-Oxide (9Ci) is a specialized fluorinated pyridine N-oxide derivative, identified by CAS NO 303154-04-3. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for introducing difluoropyridyl motifs into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or possessing anti-infective properties.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the difluoropyridine moiety enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for designing novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials requiring fluorinated heterocyclic components.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	Pyridine, 2,4-Difluoro-, 1-Oxide (9Ci)
CAS No.	303154-04-3
Molecular Formula	C5H3F2NO
Molecular Weight	131.08 g/mol
Synonyms	2,4-Difluoropyridine 1-Oxide; 2,4-Difluoropyridine N-Oxide; 2,4-Difluoropyridin-1-ium-1-olate; 2,4-Difluoropyridine-1-oxide; 1-Oxido-2,4-difluoropyridin-1-ium; 2,4-Difluoro-1-oxidopyridin-1-ium; 2,4-Difluoropyridinium-1-olate
EINECS	Contact for details

Quality Control

Our Pyridine, 2,4-Difluoro-, 1-Oxide (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.