Description

Pyridine, 2,3-Difluoro-, 1-Oxide (9Ci) is a fluorinated pyridine N-oxide derivative, a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring both fluorine substituents and an N-oxide moiety, makes it a critical intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, where its fluorine atoms can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for designing specialized ligands in transition metal catalysis, enabling more efficient and selective synthetic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require specific fluorine-based properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes to study biological systems and mechanisms.

Basic Information

Product Name	Pyridine, 2,3-Difluoro-, 1-Oxide (9Ci)
CAS No.	303154-03-2
Molecular Formula	C5H3F2NO
Molecular Weight	131.08 g/mol
Synonyms	2,3-Difluoropyridine 1-Oxide; 2,3-Difluoropyridine N-Oxide; 2,3-Difluoropyridine-1-oxide; 1-Oxido-2,3-difluoropyridin-1-ium; 2,3-Difluoropyridin-1-ium-1-olate; 2,3-Difluoropyridine Oxide; 2,3-Difluoro-1-oxidopyridin-1-ium
EINECS	Contact for details

Quality Control

Our Pyridine, 2,3-Difluoro-, 1-Oxide (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles and ISO-aligned processes guarantees batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.