Description

1-Acetyl-1H-Indole-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophile for introducing the 1-acetylindole-5-sulfonyl moiety, enabling the creation of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used to construct advanced herbicide and pesticide molecules with enhanced efficacy and selectivity.
• Material Science: Building block for creating specialized polymers or dyes with unique optical or electronic properties.
• Chemical Biology Probes: Employed in the development of activity-based probes for studying protein function and biological pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical suppliers for bespoke compound libraries.

Basic Information

Product Name	1-Acetyl-1H-Indole-5-Sulfonyl Chloride
CAS No.	303019-19-4
Molecular Formula	C10H8ClNO3S
Molecular Weight	257.69 g/mol
Synonyms	1-Acetyl-5-indolesulfonyl chloride; 5-(Chlorosulfonyl)-1-acetyl-1H-indole; 1H-Indole-5-sulfonyl chloride, 1-acetyl-; 1-Acetylindole-5-sulfonyl chloride; N-Acetyl-5-indolesulfonyl chloride; 5-(Chlorosulfonyl)-N-acetylindole; 1-Acetyl-5-sulfonylchloride indole; 303019-19-4
EINECS	Contact for details

Quality Control

Our production of 1-Acetyl-1H-Indole-5-Sulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.