Description

4-(3,5-Difluorophenyl)-4-Oxobutyric Acid is a high-purity fluorinated organic building block of significant importance in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its difluorophenyl moiety is crucial for modulating biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors engaged in the synthesis of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where fluorine substitution enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated monomers or ligands in the creation of specialized polymers and catalysts.
• Organic Synthesis: A versatile reagent for constructing complex molecular architectures via reactions at the ketone and carboxylic acid functional groups.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-(3,5-Difluorophenyl)-4-Oxobutyric Acid
CAS No.	302912-30-7
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	4-Oxo-4-(3,5-difluorophenyl)butanoic acid; 3,5-Difluoro-γ-oxobenzenebutanoic acid; 4-(3,5-Difluorobenzoyl)butyric acid; γ-Oxo-3,5-difluorobenzenebutanoic acid; Butanoic acid, 4-oxo-4-(3,5-difluorophenyl)-; 302912-30-7; 4-(3,5-Difluorophenyl)-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our 4-(3,5-Difluorophenyl)-4-Oxobutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.