Description

4-Nitro-3-(Trifluoromethyl)Benzenesulfonylchloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and electron-withdrawing nitro and trifluoromethyl groups. This compound matters for its critical role in synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors where its unique structure imparts desirable properties to final products. It is primarily needed by research chemists and process development scientists working on sulfonamide-based active ingredients, specialty dyes, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that benefit from the stability and bioactivity of the trifluoromethyl and sulfonamide groups.
• Specialty Chemical Production: Serves as a precursor for dyes, pigments, and functional materials requiring specific electronic or steric properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Polymer Modification: Can be used to introduce sulfonamide functionalities into polymer chains to alter solubility, adhesion, or other material characteristics.

Basic Information

Product Name	4-Nitro-3-(Trifluoromethyl)Benzenesulfonylchloride
CAS No.	301856-45-1
Molecular Formula	C7H3ClF3NO4S
Molecular Weight	289.61 g/mol
Synonyms	3-(Trifluoromethyl)-4-nitrobenzenesulfonyl chloride; 4-Nitro-α,α,α-trifluoro-m-toluenesulfonyl chloride; 1-Nitro-2-(trifluoromethyl)-5-(chlorosulfonyl)benzene; 2-(Trifluoromethyl)-4-nitrobenzenesulfonyl chloride; 4-Nitro-3-trifluoromethylbenzenesulfonyl chloride; NSC 405124; Benzenesulfonyl chloride, 4-nitro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Nitro-3-(Trifluoromethyl)Benzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.