Description

Apcin CAS NO 300815-04-7 is a specialized chemical compound used as a potent and selective inhibitor of the anaphase-promoting complex/cyclosome (APC/C). This compound is critical for researchers investigating cell cycle regulation, mitotic exit, and protein degradation pathways. It is primarily utilized in life science research, pharmaceutical development, and biochemical studies where precise control of the cell cycle is required.

Application

• Cell Cycle Research: A key tool for studying the mechanisms of mitosis, chromosome segregation, and the transition from metaphase to anaphase.
• Cancer Biology Studies: Used to investigate the role of APC/C dysregulation in tumorigenesis and to evaluate potential therapeutic targets.
• Biochemical Assay Development: Serves as a reference standard and active component in high-throughput screening assays for drug discovery.
• Academic & Pharmaceutical R&D: Enables fundamental research into protein degradation, ubiquitination pathways, and cell fate decisions.
• Mechanistic Studies: Applied to dissect the specific functions of APC/C co-activators Cdc20 and Cdh1 in various cellular contexts.

Basic Information

Product Name	Apcin
CAS No.	300815-04-7
Molecular Formula	C₁₄H₁₀ClN₃O₂
Molecular Weight	287.70 g/mol
Synonyms	APC Inhibitor; Apcin; (2Z)-2-[(4-Chlorophenyl)methylidene]-4-oxo-1,3-thiazolidine-5-carboxylic acid; 2-[(4-Chlorobenzylidene)-4-oxothiazolidine-5-carboxylic acid; 2-(4-Chlorobenzylidene)-4-oxo-1,3-thiazolidine-5-carboxylic acid; APC/C Inhibitor; Cdc20-APC Inhibitor
EINECS	Contact for details

Quality Control

Our Apcin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.