Description

3-Fluoro-5-Formylpyridine is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a formyl group and a fluorine atom on the pyridine ring, makes it an essential precursor for constructing complex molecules with tailored properties. This compound is particularly valuable for pharmaceutical R&D, agrochemical development, and materials science, where it is used to introduce key functional groups and modulate electronic characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and scaffold diversification.
• Fluorinated Fine Chemicals: Acts as a starting material for producing other fluorinated fine chemicals and specialty additives.

Basic Information

Product Name	3-Fluoro-5-Formylpyridine
CAS No.	39891-04-8
Molecular Formula	C6H4FNO
Molecular Weight	125.10 g/mol
Synonyms	5-Formyl-3-fluoropyridine; 3-Fluoro-5-pyridinecarboxaldehyde; 3-Fluoropyridine-5-carboxaldehyde; 3-Fluoro-5-pyridylcarboxaldehyde; 3-Fluoropyridine-5-carbaldehyde; 5-Aldehydro-3-fluoropyridine; Pyridine, 3-fluoro-5-formyl-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Formylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated industries, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.