Description

(3Ar,4R,5R,6As)-Hexahydro-5-Hydroxy-4-(3-Oxo-1-Decenyl)-2H-Cyclopenta[B]Furan-2-One 5-(4-Phenylbenzoate) is a high-purity, complex organic intermediate with significant value in advanced synthetic chemistry. This compound is critical for research and development in the pharmaceutical and fine chemical sectors, where precise stereochemistry and functional group compatibility are paramount. It serves as a sophisticated building block for medicinal chemists and process development scientists targeting novel therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in prostaglandin and leukotriene analog synthesis.
• Medicinal Chemistry Research: Used as a core scaffold or advanced precursor in drug discovery programs for inflammation, cardiovascular, and respiratory targets.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the optimization and pilot-scale production of complex drug candidates.
• Academic & Institutional Research: A valuable reagent for synthetic methodology development and stereochemical studies in university and institutional laboratories.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, flavors, fragrances, and other high-value organic compounds requiring specific stereocenters.
• Biochemical Probes: Potential use in the development of molecular probes for studying enzyme mechanisms and biological pathways related to its structural class.

Basic Information

Product Name	(3Ar,4R,5R,6As)-Hexahydro-5-Hydroxy-4-(3-Oxo-1-Decenyl)-2H-Cyclopenta[B]Furan-2-One 5-(4-Phenylbenzoate)
CAS No.	39865-76-4
Molecular Formula	C30H34O5
Molecular Weight	474.59 g/mol
Synonyms	5-Hydroxy-4-(3-oxo-1-decenyl)hexahydro-2H-cyclopenta[b]furan-2-one 5-(4-phenylbenzoate); Prostaglandin Intermediate; 5-(4-Phenylbenzoyloxy) Prostaglandin F2α Derivative; (3aR,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(E)-3-oxo-1-decenyl]-2H-cyclopenta[b]furan-2-one 5-(4-phenylbenzoate); 39865-76-4; 5-O-(4-Phenylbenzoyl) Prostaglandin F2α Lactone Analog
EINECS	Contact for details

Quality Control

Our (3Ar,4R,5R,6As)-Hexahydro-5-Hydroxy-4-(3-Oxo-1-Decenyl)-2H-Cyclopenta[B]Furan-2-One 5-(4-Phenylbenzoate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.