Description

16,16-Dimethyl Prostaglandin E2 is a synthetic analog of prostaglandin E2, a key bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and potent biological activity, making it a critical research tool and a potential intermediate in pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for investigating cellular signaling pathways, inflammation, and reproductive biology.

Application

• Biomedical Research: A key tool for studying prostaglandin receptor (EP) signaling, cellular proliferation, and differentiation in vitro and in vivo.
• Pharmaceutical R&D: Serves as a reference standard and a potential synthetic intermediate in the development of novel therapeutics targeting inflammation, pain, and gastrointestinal disorders.
• Cell Culture & Toxicology: Used to modulate cellular responses, study cytoprotective effects, and investigate drug-induced toxicity models.
• Reproductive Biology Studies: Employed in research related to uterine contractility, cervical ripening, and other reproductive processes.
• Signal Transduction Pathways: Essential for elucidating the role of eicosanoids in various disease states and physiological functions.

Basic Information

Product Name	16,16-Dimethyl Prostaglandin E2
CAS No.	39746-25-3
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	16,16-Dimethyl PGE2; 16,16-Dimethylprostaglandin E2; 11α,15α-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic Acid; 16,16-Dimethyl-9-oxoprosta-5,13-dien-1-oic Acid, 11,15-dihydroxy-; DM-PGE2; 16,16-Dimethyl Prostaglandin E2 (dmPGE2); (5Z,13E)-(9S,11R,15S)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic Acid
EINECS	Contact for details

Quality Control

Our 16,16-Dimethyl Prostaglandin E2 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.