Description

2-Methyl-3-(n-Acetylcystein-S-Yl)-1,4-Naphthoquinone is a specialized synthetic naphthoquinone derivative covalently linked to N-acetylcysteine. This compound matters as a key intermediate and research chemical for developing novel bioactive molecules, particularly in the study of redox biology and targeted drug delivery systems. It is needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity fine chemicals for applications in medicinal chemistry and biochemical research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly those targeting oxidative stress pathways.
• Biochemical Research: Used as a tool compound to study the biological effects of quinone derivatives, redox cycling, and thiol-quinone interactions in cellular models.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with enhanced efficacy and reduced toxicity profiles.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Antioxidant Mechanism Studies: Investigated for its potential role as a prodrug or conjugate that can modulate glutathione levels and cellular antioxidant defenses.

Basic Information

Product Name	2-Methyl-3-(n-Acetylcystein-S-Yl)-1,4-Naphthoquinone
CAS No.	39484-05-4
Molecular Formula	C₁₆H₁₅NO₅S
Molecular Weight	333.36 g/mol
Synonyms	2-Methyl-3-(N-acetyl-L-cystein-S-yl)-1,4-naphthoquinone; 3-[(2-Acetamido-3-mercaptopropanoyl)sulfanyl]-2-methyl-1,4-naphthoquinone; NAC-Menadione Conjugate; N-Acetylcysteine Menadione Adduct; 1,4-Naphthoquinone, 2-methyl-3-[(2-acetamido-3-mercaptopropanoyl)thio]-; S-(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl) N-acetyl-L-cysteine thioester
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(n-Acetylcystein-S-Yl)-1,4-Naphthoquinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.