Description

Tityustoxin K-Alpha CAS NO 39465-37-7 is a highly specific, peptide-based neurotoxin isolated from scorpion venom. This compound is of significant value in neuroscience and pharmacological research due to its potent and selective modulation of potassium ion channels. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in ion channel studies, neurophysiology, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a critical tool for studying the structure, function, and pharmacology of voltage-gated potassium (Kv) channels.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify and characterize new ion channel modulators for neurological and cardiac conditions.
• Toxicology & Venom Studies: Serves as a reference standard for analyzing scorpion venom composition and understanding the mechanisms of envenomation.
• Academic & Institutional Research: Employed in electrophysiology experiments (e.g., patch-clamp) to investigate neuronal excitability and signal transduction pathways.
• Biomarker & Diagnostic Tool Development: Potential use in developing assays for ion channel-related diseases.
• Chemical Biology: Utilized as a molecular probe to map channel binding sites and study protein-ligand interactions.

Basic Information

Product Name	Tityustoxin K-Alpha
CAS No.	39465-37-7
Molecular Formula	C184H281N53O55S7
Molecular Weight	~4200 g/mol (monoisotopic)
Synonyms	TsTX-Kα; Tityus serrulatus toxin Kα; Potassium channel toxin α-KTx 3.7; Neurotoxin TsTX-Kα; Tityustoxin Kα; α-KTx 3.7; TsKα; Venom peptide TsTX-Kα
EINECS	Contact for details

Quality Control

Our Tityustoxin K-Alpha is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, bioactivity (where applicable), and analytical data are provided to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Specified per batch (Contact for details)
Endotoxin Level	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.