Description

Polyethylene Glycol-Glutaminase-Asparaginase is a chemically modified enzyme conjugate designed for enhanced therapeutic and research applications. This product is engineered to improve the pharmacokinetic profile and stability of the native enzyme, offering significant advantages in targeted delivery and sustained activity. It is primarily utilized by the pharmaceutical and biotechnology sectors for advanced therapeutic development, particularly in oncology and metabolic research.

Application

• Oncological Therapeutics: As a key component in enzyme replacement therapies and targeted cancer treatments, particularly for leukemia.
• Biopharmaceutical Research: Used in the development and study of novel drug delivery systems and protein-polymer conjugates.
• Metabolic Disorder Studies: Applied in research models investigating amino acid metabolism and related pathways.
• Enzyme Stabilization Platforms: Serves as a model system for developing PEGylated enzymes with improved shelf-life and in vivo performance.
• Diagnostic Reagent Formulation: Incorporated into specialized assay kits for the detection of specific amino acids or enzyme activity.

Basic Information

Product Name	Polyethylene Glycol-Glutaminase-Asparaginase
CAS No.	39335-03-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PEG-Glutaminase-Asparaginase; PEGylated Glutaminase-Asparaginase; Poly(oxy-1,2-ethanediyl)-modified L-Glutamine Amidohydrolase/L-Asparagine Amidohydrolase; Glutaminase-Asparaginase PEG Conjugate; Enzyme-Polymer Conjugate 39335-03-0; PEG-GA Conjugate; Modified Asparaginase-Glutaminase
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for biopharmaceutical intermediates. Each batch is characterized for key parameters including enzyme activity, degree of PEGylation, and purity profile. Certificates of Analysis (COA) documenting these specifications are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere if specified and stored in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (IR)	Conforms to reference standard
Protein Content (Biuret)	≥ 90%
Enzymatic Activity (Assay)	Contact for details
Degree of PEGylation (HPLC)	Contact for details
Moisture Content (KF)	≤ 5.0%
Biological Safety (Sterility)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.