Description

3,5-Dibromobenzenesulfonylchloride is a versatile and highly reactive organosulfur compound, primarily used as a key sulfonylation reagent and synthetic building block. Its value lies in its ability to introduce the sulfonyl functional group into target molecules, enabling the synthesis of complex sulfonamides and sulfonate esters. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the sulfonyl moiety enhances biological activity.
• Material Science: Serves as a precursor for creating specialized polymers, dyes, and liquid crystals with tailored properties.
• Chemical Research & Development: Employed in organic synthesis laboratories for method development and the construction of complex molecular architectures.
• Cross-Coupling Reactions: Acts as a substrate in metal-catalyzed coupling reactions (e.g., Suzuki, Stille) to create biaryl systems.
• Sulfonamide Library Synthesis: Enables high-throughput parallel synthesis for medicinal chemistry and drug discovery screening programs.

Basic Information

Product Name	3,5-Dibromobenzenesulfonylchloride
CAS No.	39213-20-2
Molecular Formula	C6H3Br2ClO2S
Molecular Weight	334.41 g/mol
Synonyms	3,5-Dibromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 3,5-dibromo-; 3,5-Dibromophenylsulfonyl chloride; 3,5-Dibromobenzene-1-sulfonyl chloride; NSC 403120; 1,3-Dibromo-5-(chlorosulfonyl)benzene; 3,5-Dibromobenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3,5-Dibromobenzenesulfonylchloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.