Description

1-(Difluoromethoxy)-3-Isocyanatobenzene is a specialized aromatic isocyanate derivative featuring a difluoromethoxy substituent. This unique molecular structure makes it a valuable building block for synthesizing advanced polymers and fine chemicals with enhanced properties. It is primarily sought after by R&D chemists and process engineers in the agrochemical and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor for the synthesis of novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve biological activity and metabolic stability.
• Pharmaceutical Building Block: Used in medicinal chemistry research to develop active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) and inflammatory diseases.
• Polymer Modification: Serves as a functional monomer for producing specialty polyurethanes and polyurea coatings with tailored surface properties, chemical resistance, and durability.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of advanced materials for electronic applications, where the fluorine atoms contribute to desired dielectric and thermal properties.
• Cross-linking Agent: Acts as a reactive cross-linker in resin systems to enhance mechanical strength and thermal stability in high-performance composites.

Basic Information

Product Name	1-(Difluoromethoxy)-3-Isocyanatobenzene
CAS No.	39139-35-0
Molecular Formula	C8H5F2NO2
Molecular Weight	185.13 g/mol
Synonyms	3-Isocyanato-1-(difluoromethoxy)benzene; m-(Difluoromethoxy)phenyl isocyanate; 1-Difluoromethoxy-3-isocyanatobenzene; 3-(Difluoromethoxy)phenyl isocyanate; Benzene, 1-(difluoromethoxy)-3-isocyanato-; Isocyanic acid, 3-(difluoromethoxy)phenyl ester
EINECS	Contact for details

Quality Control

Our production of 1-(Difluoromethoxy)-3-Isocyanatobenzene adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize stability. Due to its moisture-sensitive (hygroscopic) nature, containers must be kept sealed under a dry inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.