Description

Desmethyllevoprotiline is a key pharmaceutical intermediate and reference standard with significant importance in research and development. This compound is primarily valued for its role in the synthesis and analytical characterization of related active pharmaceutical ingredients (APIs). It is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on neuropharmacology and antidepressant drug development. The material is supplied to meet the stringent purity requirements of these advanced applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced antidepressant compounds and related APIs.
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, GC, and other chromatographic systems.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related therapeutic agents.
• Biochemical Research: Serves as a tool compound in neuroscience research to study receptor interactions and mechanisms of action.
• Impurity Standard: Used to identify, quantify, and control specified and unspecified impurities in final drug substances according to ICH guidelines.
• Custom Synthesis: A starting material for the preparation of novel derivatives and analogs in medicinal chemistry programs.

Basic Information

Product Name	Desmethyllevoprotiline
CAS No.	38990-54-4
Molecular Formula	C19H21N
Molecular Weight	263.38 g/mol
Synonyms	(-)-Desmethyllevoprotiline; (3S)-3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-N-methylpropan-1-amine; N-Methyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)propylamine; Levoprotiline Impurity; Desmethyl metabolite of Levoprotiline
EINECS	Contact for details

Quality Control

Our Desmethyllevoprotiline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profile determination via HPLC and other orthogonal methods, to ensure it meets high-purity standards suitable for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.