Description

3-(Trifluoromethyl)Phenylglyoxal Hydrate is a versatile and high-value fluorinated aromatic building block. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is a critical intermediate for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the CF₃ group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and organic electronic materials to modify electronic properties and stability.
• Fluorescent Probe and Dye Manufacturing: Acts as a core structure for developing sensitive chemical sensors and specialized dyes.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the global life sciences industry.

Basic Information

Product Name	3-(Trifluoromethyl)Phenylglyoxal Hydrate
CAS No.	38923-38-5
Molecular Formula	C₉H₅F₃O₃
Molecular Weight	218.13 g/mol
Synonyms	2-Oxo-2-[3-(trifluoromethyl)phenyl]acetaldehyde Hydrate; 3-(Trifluoromethyl)benzoylformaldehyde Hydrate; α-Oxo-3-(trifluoromethyl)benzeneacetaldehyde Hydrate; 3-Trifluoromethylphenylglyoxal Monohydrate; 1-(3-Trifluoromethylphenyl)-1,2-ethanedione Hydrate; 3-(Trifluoromethyl)phenylethanedione Hydrate; m-Trifluoromethylphenylglyoxal Hydrate
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Phenylglyoxal Hydrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.