Description

15(R)-Prostaglandin E2 is a stereoisomer of the bioactive lipid mediator Prostaglandin E2, distinguished by the R-configuration at the C-15 hydroxyl group. This specific configuration is critical for research into receptor selectivity and the development of targeted therapeutic agents. It is an essential biochemical tool for pharmaceutical R&D, particularly in studies related to inflammation, pain, and reproductive physiology.

Application

• Pharmaceutical Research & Development: A key reference standard and intermediate in the synthesis of novel anti-inflammatory drugs and targeted therapies.
• Biochemical Pathway Analysis: Used to study the specific roles of prostaglandin receptor subtypes (EP1-EP4) in cellular signaling cascades.
• Academic & Clinical Research: Fundamental for investigating physiological and pathological processes in inflammation, pain perception, fever, and vascular tone.
• Drug Discovery Screening: Serves as a high-purity ligand in assay development for screening potential drug candidates that modulate the prostaglandin pathway.
• Metabolite Standard: Employed as an analytical standard in LC-MS and HPLC methods for the quantification of prostaglandins and their metabolites in biological samples.

Basic Information

Product Name	15(R)-Prostaglandin E2
CAS No.	38873-82-4
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	15(R)-PGE2; (15R)-Prostaglandin E2; (5Z,11α,13E,15R)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; PGE2 (15R-isomer); 15R-PGE2; 15-epi-Prostaglandin E2; 15-epi-PGE2
EINECS	Contact for details

Quality Control

Every batch of 15(R)-Prostaglandin E2 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. A detailed Certificate of Analysis (COA) including HPLC purity, spectroscopic identification, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the primary container sealed under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.